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- bs-17045P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-17045P |
| 英文名称 | phospho-KIF20A (Ser528) Antibody Blocking Peptide |
| 中文名称 | 磷酸化有丝分裂驱动蛋白样2封闭多肽 |
| 英文别名 | KIF20A (phospho S528); p-KIF20A (phospho S528); GG10 2; GG10_2; Kif20a; kinesin family member 20A; Kinesin like protein KIF20A; Kinesin-like protein 174; mitotic kinesin like protein 2; MKLP2; RAB6 interacting, kinesin like (rabkinesin6); Rab6-interacting kinesin-like protein; RAB6-INTERACTING PROTEIN, KINESIN-LIKE; RAB6KIFL; Rabkinesin 6; AA415432; FLJ21151. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Cytokinesis Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin-like |
| 亚细胞定位 | Golgi apparatus (By similarity). Cytoplasm, cytoskeleton, spindle. |
| 翻译后修饰 | Phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle. |
| 相似性 | Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. |
| 功能 | Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Enables protein kinase binding activity. Involved in microtubule bundle formation; midbody abscission; and regulation of cytokinesis. Located in several cellular components, including cleavage furrow; intercellular bridge; and midbody. Implicated in restrictive cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022] |
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phospho-KIF20A (Ser528) Antibody Blocking Peptide(bs-17045P)-500ug
￥1080
