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- Bioss
- bs-2634P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2634P |
| 英文名称 | LILRB1 Antibody Blocking Peptide |
| 中文名称 | 细胞表面免疫球蛋白样转录因子2封闭多肽 |
| 英文别名 | LIRB1_HUMAN; Leukocyte immunoglobulin-like receptor subfamily B member 1; ILT2; LIR1; MIR7; LIR-1; Leukocyte immunoglobulin-like receptor 1; CD85 antigen-like family member J; Immunoglobulin-like transcript 2 (ILT-2); Monocyte/macrophage immunoglobulin-like receptor 7 (MIR-7); CD85j; |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > MHC > Class I Immunology > Immunoglobulins > Receptors |
| 亚基 | Binds PTPN6 when phosphorylated. Binds FCGR1A. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells. |
| 相似性 | Contains 4 Ig-like C2-type (immunoglobulin-like) domains. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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LILRB1 Antibody Blocking Peptide(bs-2634P)-500ug
￥880
