IL31RA Antibody Blocking Peptide(bs-2631P)-500ug

IL31RA Antibody Blocking Pepti

de(bs-2631P)-500ug
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  • ￥880
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  • bs-2631P
  • 2025年10月16日
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    北京博奥森生物技术有限公司
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      500ug

    产品编号bs-2631P
    英文名称IL31RA Antibody Blocking Peptide
    中文名称白介素31受体a封闭多肽
    英文别名Interleukin-31 receptor subunit alpha; interleukin-31 receptor subunit alpha precursor; cytokine receptor NR10; mGLM-R; IL-31RA; zcytoR17; IL-31R-alpha; gp130-like receptor; IL-31R subunit alpha; novel cytokine receptor 10; IL-31 receptor subunit alpha; gp130-like monocyte receptor; interleukin 31RA; class I cytokine receptor; Il31ra; CRL3; CRL 3; GLM-R; Glmr; GPL; NR10; HGLM R; HGLMR; IL 31RA; IL31RA; Interleukin 31 receptor A; MGC125346; PRO21384; Soluble type I cytokine receptor CRL3; IL31R_HUMAN.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > STATs

    Immunology > Innate Immunity > Cytokines > Interleukins

    Signal Transduction > Signaling Pathway > Nuclear Signaling > STATs

    亚基Heterodimer with OSMR. Interacts with JAK1 and STAT3.
    亚细胞定位Cell membrane; Single-pass type I membrane protein (Probable).
    组织特异性Expressed at low levels in testis, ovary, brain, prostate, placenta, thymus, bone marrow, trachea and skin. Detected in all of the myelomonocytic lineage. Expressed in CD14-and CD56-positive blood cells and by macrophages (at protein level).
    翻译后修饰N-glycosylated.
    相似性Belongs to the type I cytokine receptor family. Type 2 subfamily.
    Contains 5 fibronectin type-III domains.
    功能Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料IL31RA is related to gp130 (IL6ST; MIM 600694), the common receptor subunit for IL6 (MIM 147620)-type cytokines. Oncostatin M receptor (OSMR; MIM 601743) and IL31RA form the heterodimeric receptor through which IL31 (MIM 609509) signals. Expression of IL31RA and OSMR mRNA is induced in activated monocytes, and both mRNAs are constitutively expressed in epithelial cells (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM].

     

     

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