- ￥880
- Bioss
- bs-2629P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2629P |
| 英文名称 | IFNL1 Antibody Blocking Peptide |
| 中文名称 | 白细胞介素29封闭多肽 |
| 英文别名 | Interleukin-29; IL-29; IL 29; IL29; Interferon lambda-1; Cytokine ZCYTO21; IFN lambda 1; IFNL1; Interferon lambda 1; IFNL1_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the IL-28/IL-29 family. |
| 功能 | Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IL-29 belongs to the type III interferon protein family, which is distinct from the type I IFNs. IL29 is induced by virus infection or double stranded RNA. IL-29 acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. IL-29 has antiviral, antitumour and immunomodulatory activities. IL-29 is primarily active in epithelial cells and this cell type selective action is because of the epithelial cell specific expression of its receptor IFNLR1. It also exerts an immunomodulatory effect by up regulating MHC class I antigen expression. This recombinant human IL-29 is produced by human cells.(Tag free) Biological activity: The activity was measured by its antivirus function in A549 cells (human lung adenocarcinoma epithelial cell line) infected with encephalomyocarditis (EMC) virus. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. |
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IFNL1 Antibody Blocking Peptide(bs-2629P)-500ug
￥880
