- ￥880
- Bioss
- bs-2625P
- 2025年10月16日
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- 详细信息
- 技术资料
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500ug
| 产品编号 | bs-2625P |
| 英文名称 | IL22RA2 Antibody Blocking Peptide |
| 中文名称 | 白介素22受体结合蛋白封闭多肽 |
| 英文别名 | IL22RA2; Interleukin-22 receptor subunit alpha-2; IL-22 receptor subunit alpha-2; IL-22R-alpha-2; IL-22RA2; Interleukin-22-binding protein; IL-22BP; IL22BP; Cytokine receptor family 2 member 10; CRF2-10; Cytokine receptor class-II member 10; Cytokine receptor family type 2, soluble 1; CRF2-S1; ZcytoR16; I22R2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Cytokines > Interleukins |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach. |
| 相似性 | Belongs to the type II cytokine receptor family.
Contains 3 fibronectin type-III domains. |
| 功能 | Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | There are two isoforms of IL22 RA2 produce by alternative splicing. Isoform 1 may play a role in establishing and maintaining successful pregnancy. Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). It may play an important role as an IL22 antagonist in the regulation of inflammatory responses. |
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IL22RA2 Antibody Blocking Peptide(bs-2625P)-500ug
￥880
