- ￥880
- Bioss
- bs-2615P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2615P |
| 英文名称 | IL18R1 Antibody Blocking Peptide |
| 中文名称 | 白细胞介素-18受体α链封闭多肽 |
| 英文别名 | interleukin-18 receptor alpha chain; Interleukin-18 receptor 1; IL-18R-1; IL-18R1; IL1 receptor-related protein; interleukin 1 receptor-like protein; IL-1Rrp; IL1R-rp; CD218 antigen-like family member A; CD218a; CDw218; CDw218a; CDw218a antigen; IL18RA; Il18ralpha; IL1RRP; interleukin 18 receptor 1. |
| 纯化方法 | HPLC |
| 亚基 | Does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines. |
| 相似性 | Belongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 TIR domain. |
| 功能 | Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
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IL18R1 Antibody Blocking Peptide(bs-2615P)-500ug
￥880
