SST 14 Antibody Blocking Peptide(bs-11796P)-500ug

SST 14 Antibody Blocking Pepti

de(bs-11796P)-500ug
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  • bs-11796P
  • 2025年10月16日
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      500ug

    产品编号bs-11796P
    英文名称SST 14 Antibody Blocking Peptide
    中文名称生长抑素14封闭多肽
    英文别名Growth hormone release inhibiting factor; SMS_HUMAN; SMST; SST; Somatostatin 14; Somatostatin14; Somatostatin-14; somatostatin SS14; Somatostatin 28; Somatostatin28; Somatostatin-28; somatostatin SS28.
    纯化方法HPLC
    研究领域

    Developmental Biology > Lineage specification > Endoderm

    Neuroscience > Neurology process > Neuroendocrinology > GH Regulation

    Neuroscience > Neurotransmitter > Neuropeptides > Hormones

    Stem Cells > Lineage Markers > Endoderm

    亚细胞定位Secreted.
    相似性Belongs to the somatostatin family.
    功能The cyclic tetradecapeptide somatostatin is widely distributed throughout the body and is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high affinity receptors on the cell surface. Somatostatin inhibits the release of somatotropin. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid. Somatostatin positive cells may also be present in medullary thyroid carcinomas, C cell hyperplasia, thymic and lung tumors and pulmonary small cell carcinomas.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Somatostatin is a regulatory hormone that is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G protein-coupled somatostatin receptors. This cyclic tetradecapeptide inhibits the secretion of many important hormones, including somatotropin (also designated growth hormone, or GH), insulin and glucagon. Somatostatin is found in both the hypothalamus and pancreas. Somatostatin is thought to be involved in the regulation of insulin synthesis. The hormone somatostatin has active 14 amino acid and 28 amino acid forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. In the cerebellum, Somatostatin-14 and Somatostatin-28 are highly expressed at birth and in the adult stage, respectively. Somatostatin affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. The gene encoding Somatostatin maps to human chromosome 3q28.

     

     

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