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- Bioss
- bs-14288P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14288P |
| 英文名称 | DFNB31 Antibody Blocking Peptide |
| 中文名称 | 常染色体隐性遗传性耳聋型31蛋白封闭多肽 |
| 英文别名 | 1110035G07Rik; Autosomal recessive deafness type 31 protein; CASK interacting protein CIP98; CIP 98; CIP98; Deafness autosomal recessive 31; DFNB 31; DKFZp434N014; KIAA1526; RP11 9M16.1; USH 2D; USH2D; Whirlin; WHRN; WHRN_HUMAN; WI. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Sensory System > Auditory system Neuroscience > Sensory System > Visual system |
| 亚细胞定位 | Cytoplasm. Cell projection > stereocilium. Cell projection > growth cone. Detected at the level of stereocilia in inner outer hair cells of the cochlea and vestibule. Co-localizes with the growing ends of actin filaments (By similarity). Colocalizes with MPP1 in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium. |
| 相似性 | Contains 3 PDZ (DHR) domains. |
| 功能 | Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Mar 2010] |
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DFNB31 Antibody Blocking Peptide(bs-14288P)-500ug
￥880
