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- Bioss
- bs-14279P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-14279P |
| 英文名称 | DERA Antibody Blocking Peptide |
| 中文名称 | 脱氧核糖磷酸醛缩酶样封闭多肽 |
| 英文别名 | Deoxyriboaldolase; 2 deoxyribose 5 phosphate aldolase homolog C. elegans; CGI 26; CGI26; CGI-26; DEOC; DEOC_HUMAN; Deoxyriboaldolase; Deoxyribose phosphate aldolase like; DERA; Phosphodeoxyriboaldolase; Putative deoxyribose phosphate aldolase; Putative deoxyribose-phosphate aldolase. |
| 纯化方法 | HPLC |
| 相似性 | Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily. |
| 功能 | Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DERA is a 318 amino acid member of the deoC/fbaB aldolase protein family. Involved in the carbohydrate degradation pathway, DERA catalyzes the conversion of 2-deoxy-D-ribose 5-phosphate to D-glyceraldehyde 3-phosphate and an acetyldehyde. The gene that encodes DERA maps to human chromosome 12, which encodes over 1,100 genes within 132 million bases, making up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. |
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DERA Antibody Blocking Peptide(bs-14279P)-500ug
￥880
