- ￥880
- Bioss
- bs-14269P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-14269P |
| 英文名称 | DENND1A Antibody Blocking Peptide |
| 中文名称 | DENND1A蛋白封闭多肽 |
| 英文别名 | Connecdenn 1; Connecdenn; DEN1A_HUMAN; DENN domain-containing protein 1A; DENN/MADD domain containing 1A; dennd1a; FAM31A; FLJ21129; FLJ38464; KIAA1608; OTTHUMP00000022090; Protein FAM31A; RP11 230L22.3. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell junction > synapse > presynaptic cell membrane. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Also associated with uncoated vesicles. |
| 相似性 | Contains 1 dDENN domain. Contains 1 DENN domain. Contains 1 uDENN domain. |
| 功能 | Guanine nucleotide exchange factor (GEF) for RAB35. May be involved in the clathrin-mediated endocytosis of synaptic vesicles. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010] |
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DENND1A Antibody Blocking Peptide(bs-14269P)-500ug
￥880
