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500ug
| 产品编号 | bs-0539P |
| 英文名称 | CGA Antibody Blocking Peptide |
| 中文名称 | 嗜铬粒素A封闭多肽 |
| 英文别名 | beta Granin; CGA; CHG A; CHGA; Chromogranin A parathyroid secretory protein 1; Chromogranin A precursor; ChromograninA; Pancreastatin; Parastatin; Parathyroid secretory protein 1; Pituitary secretory protein I; SP I; SP1; SPI; Vasostatin; ER-37; CMGA_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > Insulin and insulin-like Cancer > Tumor biomarkers Neuroscience > Cell Type Marker > Neuron marker > Soma marker Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚基 | Interacts with SCG3. |
| 亚细胞定位 | Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle membrane. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. |
| 翻译后修饰 | Sulfated on tyrosine residues and/or contains sulfated glycans.
O-glycosylated with core 1 or possibly core 8 glycans. |
| 相似性 | Belongs to the chromogranin/secretogranin proteinfamily. |
| 功能 | Pancreastatin strongly inhibits glucose induced insulin release from the pancreas. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008]. |
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CGA Antibody Blocking Peptide(bs-0539P)-500ug
¥800







