CGA Antibody Blocking Peptide(bs-0539P)-500ug

CGA Antibody Blocking Peptide(

bs-0539P)-500ug
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  • bs-0539P
  • 2025年10月16日
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      500ug

    产品编号bs-0539P
    英文名称CGA Antibody Blocking Peptide
    中文名称嗜铬粒素A封闭多肽
    英文别名beta Granin; CGA; CHG A; CHGA; Chromogranin A parathyroid secretory protein 1; Chromogranin A precursor; ChromograninA; Pancreastatin; Parastatin; Parathyroid secretory protein 1; Pituitary secretory protein I; SP I; SP1; SPI; Vasostatin; ER-37; CMGA_HUMAN.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cancer > Growth factors > Insulin and insulin-like

    Cancer > Tumor biomarkers

    Neuroscience > Cell Type Marker > Neuron marker > Soma marker

    Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like

    Tags & Cell Markers > Cell Type Markers > Tumor Associated

    亚基Interacts with SCG3.
    亚细胞定位Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle membrane. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions.
    翻译后修饰Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
    相似性Belongs to the chromogranin/secretogranin proteinfamily.
    功能Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008].

     

     

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