- ￥880
- Bioss
- bs-15563P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15563P |
| 英文名称 | IFT46 Antibody Blocking Peptide |
| 中文名称 | 细胞纤毛内转运同源蛋白46封闭多肽 |
| 英文别名 | C11orf2; C11orf60; IFT46; IFT46_HUMAN; Intraflagellar transport protein 46 homolog. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > MT Associated Proteins > MAP |
| 亚基 | Part of the IFT complex B. Interacts with IFT57, IFT88 and DAW1 (By similarity). |
| 亚细胞定位 | Cytoplasm, cytoskeleton, cilium basal body (By similarity). Cell projection, cilium (By similarity). Note=Expression is concentrated at the cilium basal body but is also detected along the length of the cilium (By similarity). |
| 相似性 | Belongs to the IFT46 family. |
| 功能 | Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IFT46 is a 304 amino acid protein that belongs to the IFT46 family. IFT46 localizes to the cilium basal body but can also be found along the length of the cilium and is a part of a complex involved in intraflagellar transport (IFT). In addition, IFT46 is involved in the bi-directional movement of particles that is required for the assembly, maintenance, and functionality of primary cilia. Furthermore, IFT46 may be involved in skeletogenesis and chondrocyte maturation. Two isoforms exist due to alternate splicing events and the gene encoding IFT46 maps to human chromosome 11. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. |
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IFT46 Antibody Blocking Peptide(bs-15563P)-500ug
￥880
