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| 规格: | 100ug | 产品价格: | ¥2280.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥6880.0 |
| 规格: | 20ug | 产品价格: | ¥680.0 |
| 产品编号 | bs-43100P |
| 英文名称 | Recombinant human PRL-R protein, C-His (HEK293) |
| 中文名称 | 重组人泌乳素受体蛋白 |
| 英文别名 | Lactogen receptor; MGC105486; OPR; Pr-1; Pr-3; PRL R; PRL-R; PRLR; Prlr-rs1; PRLR_HUMAN; Prolactin receptor a; Prolactin receptor; Prolactin receptor delta 7/11; RATPRLR; Secreted prolactin binding protein; Truncated testis-specific box 1-C prolactin receptor; wu:fj65c07; AI987712; CLONE SPM213; CPRLP; Delta 4-delta 7/11 truncated prolactin receptor; Delta 4-SF1b truncated prolactin receptor; hPRL receptor; hPRLrI; Recombinant human PRL-R protein, C-His (HEK293) |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 26.4 |
| 实际分子量 | 36 kDa |
| 浓度 | >0.5 mg/ml |
| 储存液 | PBS (pH7.4). |
| 研究领域 | Metabolism > Types of disease > Cancer Signal Transduction > Growth Factors/Hormones > Hormones Signal Transduction > Metabolism > Lipid metabolism Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases |
| 亚基 | Homodimer upon hormone binding. Interacts with SMARCA1. Interacts with GH1. Interacts with CSH. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. Isoform 7: Secreted. |
| 组织特异性 | Expressed in breast, placenta, kidney, liver and pancreas. |
| 相似性 | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains. |
| 功能 | This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]. |

The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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Recombinant human PRL-R protein, C-His (HEK293)(bs-43100P)-100ug/500ug/20ug
¥680 - 6880







