Recombinant human PRL-R protein, C-His (HEK293)(bs-43100P)-100ug/500ug/20ug

Recombinant human PRL-R protei

n, C-His (HEK293)(bs-43100P)-100ug/500ug/20ug
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  • ¥680 - 6880
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  • bs-43100P
  • 2025年10月16日
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      100ug/500ug/20ug

    规格:100ug产品价格:¥2280.0
    规格:500ug产品价格:¥6880.0
    规格:20ug产品价格:¥680.0
    产品编号bs-43100P
    英文名称Recombinant human PRL-R protein, C-His (HEK293)
    中文名称重组人泌乳素受体蛋白
    英文别名Lactogen receptor; MGC105486; OPR; Pr-1; Pr-3; PRL R; PRL-R; PRLR; Prlr-rs1; PRLR_HUMAN; Prolactin receptor a; Prolactin receptor; Prolactin receptor delta 7/11; RATPRLR; Secreted prolactin binding protein; Truncated testis-specific box 1-C prolactin receptor; wu:fj65c07; AI987712; CLONE SPM213; CPRLP; Delta 4-delta 7/11 truncated prolactin receptor; Delta 4-SF1b truncated prolactin receptor; hPRL receptor; hPRLrI; Recombinant human PRL-R protein, C-His (HEK293)
    性状Lyophilized or Liqui
    纯化方法AC
    理论分子量26.4
    实际分子量36 kDa
    浓度>0.5 mg/ml
    储存液PBS (pH7.4).
    研究领域

    Metabolism > Types of disease > Cancer

    Signal Transduction > Growth Factors/Hormones > Hormones

    Signal Transduction > Metabolism > Lipid metabolism

    Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases

    亚基Homodimer upon hormone binding. Interacts with SMARCA1. Interacts with GH1. Interacts with CSH. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
    亚细胞定位Membrane; Single-pass type I membrane protein. Isoform 7: Secreted.
    组织特异性Expressed in breast, placenta, kidney, liver and pancreas.
    相似性Belongs to the type I cytokine receptor family. Type 1 subfamily.
    Contains 2 fibronectin type-III domains.
    功能This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
    保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011].

     

     

    Recombinant human PRL-R protei
    The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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    ¥680 - 6880