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500ug
| 产品编号 | bs-13028P |
| 英文名称 | DPP10 Antibody Blocking Peptide |
| 中文名称 | 二肽基肽酶10封闭多肽 |
| 英文别名 | Dipeptidyl peptidase 10; Dipeptidyl peptidase 10 non functional; Dipeptidyl peptidase IV related protein 3; Dipeptidyl peptidase IV-related protein 3; Dipeptidyl peptidase like protein 2; Dipeptidyl peptidase X; Dipeptidyl peptidase-like protein 2; Dipeptidylpeptidase 10; DPL 2; DPL2; DPP 10; DPP X; Dpp10; DPP10_HUMAN; DPPY; DPRP 3; DPRP-3; DPRP3; Inactive dipeptidyl peptidase 10; KIAA1492. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Serine protease > DPPs |
| 亚基 | May form oligomers. Interacts with KCND1 (Probable). Interacts with KCND2. |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands. |
| 翻译后修饰 | N-glycosylated. |
| 相似性 | Belongs to the peptidase S9B family. DPPIV subfamily. |
| 功能 | Has no dipeptidyl aminopeptidase activity. May modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP10 (dipeptidyl-peptidase 10), also known as DPRP3 (dipeptidyl peptidase IV-related protein 3), DPL2 or DPPY, is a non-functional dipeptidyl peptidase which can bind to the potassium channels KV4.1 and KV4.2. It is a single-pass type II membrane protein expressed in spinal cord, adrenal glands, pancreas and brain tissues and may act as a modulator for cell surface expression and activity of KV4.1 and KV4.2. |
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DPP10 Antibody Blocking Peptide(bs-13028P)-500ug
¥880







