- ￥880
- Bioss
- bs-15558P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15558P |
| 英文名称 | IFT122 Antibody Blocking Peptide |
| 中文名称 | 细胞纤毛内转运同源蛋白122封闭多肽 |
| 英文别名 | CED; IF122_HUMAN; IFT122; Intraflagellar transport 122 homolog (Chlamydomonas); Intraflagellar transport protein 122 homolog; SPG; WD repeat domain 10; WD repeat-containing protein 10; WD repeat-containing protein 140; WDR10; WDR10p; WDR140. |
| 纯化方法 | HPLC |
| 亚基 | Component of the IFT complex A (IFT-A) complex. |
| 亚细胞定位 | Cytoplasm. Cell projection, cilium (By similarity). Cytoplasm, cytoskeleton, cilium basal body (By similarity). Note=Localizes to photoreceptor connecting cilia (By similarity). |
| 组织特异性 | Expressed in many tissues. Predominant expression in testis and pituitary. |
| 相似性 | Contains 7 WD repeats. |
| 功能 | Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | IFT122 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
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IFT122 Antibody Blocking Peptide(bs-15558P)-500ug
￥880
