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500ug
| 产品编号 | bs-21564P |
| 英文名称 | glutathione reductase Antibody Blocking Peptide |
| 中文名称 | 谷胱甘肽还原酶封闭多肽 |
| 英文别名 | glutathione reductase; GLUR; Glutathione reductase mitochondrial; GR; Gr1; GRase; GRD 1; GRD1; GSR; MGC78522; GSHR_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress Signal Transduction > Metabolism > Mitochondrial |
| 亚基 | Homodimer; disulfide-linked. |
| 亚细胞定位 | Isoform Mitochondrial: Mitochondrion.
Isoform Cytoplasmic: Cytoplasm. |
| 相似性 | Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. |
| 功能 | Maintains high levels of reduced glutathione in the cytosol. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | bs-0837P is one synthetic peptide derived from human Glutathione Reductase. Glutathione reductase (GR) is a member of pyridine nucleotide- disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+?2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis. |
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glutathione reductase Antibody Blocking Peptide(bs-21564P)-500ug
¥880







