glutathione reductase Antibody Blocking Peptide(bs-21564P)-500ug

glutathione reductase Antibody

Blocking Peptide(bs-21564P)-500ug
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  • ¥880
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  • bs-21564P
  • 2025年10月16日
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      500ug

    产品编号bs-21564P
    英文名称glutathione reductase Antibody Blocking Peptide
    中文名称谷胱甘肽还原酶封闭多肽
    英文别名glutathione reductase; GLUR; Glutathione reductase mitochondrial; GR; Gr1; GRase; GRD 1; GRD1; GSR; MGC78522; GSHR_HUMAN.
    纯化方法HPLC
    研究领域

    Cell Biology > Other Antibodies > Oxidative Stress

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress

    Signal Transduction > Metabolism > Mitochondrial

    亚基Homodimer; disulfide-linked.
    亚细胞定位Isoform Mitochondrial: Mitochondrion.
    Isoform Cytoplasmic: Cytoplasm.
    相似性Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
    功能Maintains high levels of reduced glutathione in the cytosol.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料bs-0837P is one synthetic peptide derived from human Glutathione Reductase. Glutathione reductase (GR) is a member of pyridine nucleotide- disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+?2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.

     

     

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