PPT2 Antibody Blocking Peptide(bs-11750P)-500ug

PPT2 Antibody Blocking Peptide

(bs-11750P)-500ug
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  • ¥880
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  • bs-11750P
  • 2025年10月16日
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      500ug

    产品编号bs-11750P
    英文名称PPT2 Antibody Blocking Peptide
    中文名称棕榈酰蛋白水解酶2封闭多肽
    英文别名Lysosomal thioesterase PPT2; Palmitoyl protein hydrolase 2; Palmitoyl protein thioesterase 2; PPT 2; PPT-2; Ppt2; PPT2_HUMAN; S thioesterase G14; S-thioesterase G14.
    纯化方法HPLC
    亚细胞定位Lysosome.
    组织特异性Broadly expressed, with highest levels in skeletal muscle.
    相似性Belongs to the palmitoyl-protein thioesterase family.
    功能Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料PPT2 (palmitoyl-protein thioesterase 2), also known as G14, is a 302 amino acid glycosylated protein that localizes to the lysosome and belongs to the palmitoyl-protein thioesterase family. Expressed throughout the body with highest levels in skeletal muscle, PPT2 functions to remove thioester-linked fatty acyl groups from a variety of substrates, including S-palmitoyl-CoA, thereby playing an important role in lipid metabolism. PPT2 operates at an optimal pH of 7 and exhibits the highest activity for the acyl groups on myristic and palmitic acids, with lower levels of activity toward other short- and long-chain acyl substrates. PPT2 exists as two isoforms, one of which is expressed at low levels and is catalytically inactive.

     

     

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