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- Bioss
- bs-21592P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-21592P |
| 英文名称 | FOXD2 Antibody Blocking Peptide |
| 中文名称 | 叉头蛋白D2封闭多肽 |
| 英文别名 | Drosphilia Forkhead Homolog Like 17; FKHL 17; Forkhead box protein D2; Forkhead Related Activator 9; Forkhead-related protein FKHL17; Forkhead-related transcription factor 9; FOXD2; FOXD2_HUMAN; FREAC 9; FREAC-9. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Kidney specific. |
| 相似性 | Contains 1 fork-head DNA-binding domain. |
| 功能 | Probable transcription factor involved in embryogenesis and somatogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. FOXD1 (also designated Brain Factor 2 or BF-2) is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NF-AT and NFkB. Deficiency of FOXD1 results in multiorgan, systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation. |
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FOXD2 Antibody Blocking Peptide(bs-21592P)-500ug
￥880
