- ￥880
- Bioss
- bs-17041P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-17041P |
| 英文名称 | KIF16B Antibody Blocking Peptide |
| 中文名称 | 驱动蛋白家族成员16B封闭多肽 |
| 英文别名 | Chromosome 20 open reading frame 23; Kinesin like motor protein C20orf23; SNX23; KI16B_HUMAN; Sorting nexin 23. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin-like Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation Tags & Cell Markers > Subcellular Markers > Cytoskeleton > Microtubules |
| 亚基 | Interacts with RAB14 (By similarity). Interacts with PTPN21. |
| 亚细胞定位 | Cytoplasm, cytoskeleton {ECO:0000305}. Early endosome membrane. Note=It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14. |
| 组织特异性 | Primarily expressed in brain. Also present in kidney, liver, intestine, placenta, leukocytes, heart and skeletal muscle (at protein level). |
| 翻译后修饰 | Isoform 4 is ubiquitinated at Lys-685. |
| 相似性 | Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Contains 1 FHA domain. {ECO:0000305}. Contains 1 kinesin motor domain. Contains 1 PX (phox homology) domain. |
| 功能 | Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KIF16B belongs to the kinesin like protein family. It may be involved in several stages of intracellular trafficking and is a probable microtubule dependent motor protein. |
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KIF16B Antibody Blocking Peptide(bs-17041P)-500ug
￥880
