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500ug
| 产品编号 | bs-2523P |
| 英文名称 | CD99 antigen Antibody Blocking Peptide |
| 中文名称 | CD99封闭多肽 |
| 英文别名 | T-cell surface glycoprotein E; T cell surface glycoprotein E2 precursor; 12E7; Antigen identified by monoclonal 12E7 Y homolog; Antigen identified by monoclonal antibodies 12E7 F21 and O13; CD 99; CD99 antigen; CD99 molecule; CD99X; E2 antigen; Ewing Sarcoma; MIC 2; MIC 2X; MIC 2Y; MIC2; MIC2X; MIC2Y; Monoclonal antibody 12E7; MSK5X; Protein MIC2; Surface antigen MIC2. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Invasion/microenvironment > ECM > Cell adhesion Immunology > Adaptive Immunity > T Cells > CD Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > T Cell Adhesion |
| 亚基 | Homodimer. Interacts with PILRB. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Natural killer cells. |
| 相似性 | Belongs to the CD99 family. |
| 功能 | Involved in T-cell adhesion processes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016] |
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CD99 antigen Antibody Blocking Peptide(bs-2523P)-500ug
¥880







