CD72 Antibody Blocking Peptide(bs-2517P)-500ug

CD72 Antibody Blocking Peptide

(bs-2517P)-500ug
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  • ¥880
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  • bs-2517P
  • 2025年10月16日
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      500ug

    产品编号bs-2517P
    英文名称CD72 Antibody Blocking Peptide
    中文名称CD72蛋白封闭多肽
    英文别名B-cell differentiation antigen CD72; CD72b; LYB2; B cell differentiation antigen CD72; CD72 antigen; CD72 molecule; CD72c; Ly-19; Ly-32; Ly-m19; Lyb-2; Lyb2; LYB2, mouse, homolog of; Lymphocyte antigen 32; MGC108873; CD72_HUMAN.
    纯化方法HPLC
    研究领域

    Immunology > Adaptive Immunity > B Cells > CD

    Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage

    亚基Homodimer; disulfide-linked. Associates with CD5. Interacts (tyrosine phosphorylated) with PTPN6/SHP-1 (By similarity).
    亚细胞定位Membrane; Single-pass type II membrane protein.
    组织特异性Pre-B-cells and B-cells but not terminally differentiated plasma cells.
    翻译后修饰Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1 (By similarity).
    相似性Contains 1 C-type lectin domain.
    功能Plays a role in B-cell proliferation and differentiation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface molecules such as the asialoglycoprotein receptors, CD23 and the Kupffer cell receptor. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.

     

     

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