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500ug
| 产品编号 | bs-2517P |
| 英文名称 | CD72 Antibody Blocking Peptide |
| 中文名称 | CD72蛋白封闭多肽 |
| 英文别名 | B-cell differentiation antigen CD72; CD72b; LYB2; B cell differentiation antigen CD72; CD72 antigen; CD72 molecule; CD72c; Ly-19; Ly-32; Ly-m19; Lyb-2; Lyb2; LYB2, mouse, homolog of; Lymphocyte antigen 32; MGC108873; CD72_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > B Cells > CD Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage |
| 亚基 | Homodimer; disulfide-linked. Associates with CD5. Interacts (tyrosine phosphorylated) with PTPN6/SHP-1 (By similarity). |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein. |
| 组织特异性 | Pre-B-cells and B-cells but not terminally differentiated plasma cells. |
| 翻译后修饰 | Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1 (By similarity). |
| 相似性 | Contains 1 C-type lectin domain. |
| 功能 | Plays a role in B-cell proliferation and differentiation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface molecules such as the asialoglycoprotein receptors, CD23 and the Kupffer cell receptor. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages. |
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CD72 Antibody Blocking Peptide(bs-2517P)-500ug
¥880







