NDUFS7 Antibody Blocking Peptide(bs-11734P)-500ug

NDUFS7 Antibody Blocking Pepti

de(bs-11734P)-500ug
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  • bs-11734P
  • 2025年10月16日
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      500ug

    产品编号bs-11734P
    英文名称NDUFS7 Antibody Blocking Peptide
    中文名称线粒体复合物NDUFS7蛋白封闭多肽
    英文别名CI 20; CI-20kD; Complex I 20kDa subunit; Complex I mitochondrial respiratory chain 20 KD subunit; Complex I-20kD; MGC120002; MY017; NADH coenzyme Q reductase; NADH dehydrogenase (ubiquinone) Fe S protein 7 20kDa (NADH coenzyme Q reductase); NADH dehydrogenase (ubiquinone) FeS protein 7, 20kDa (NADHcoenzyme Q reductase); NADH dehydrogenase (ubiquinone) FeS protein7, 20kDa (NADHcoenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; NADH-ubiquinone oxidoreductase 20 kDa subunit; NADH:ubiquinone oxidoreductase PSST subunit; NADHcoenzyme Q reductase; Ndufs7; NDUS7_HUMAN; PSST; PSST subunit.
    纯化方法HPLC
    研究领域

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Oxidative phosphorylation > Complex I

    Metabolism > Types of disease > Cancer

    Neuroscience > Neurology process > Neurodegenerative disease

    Signal Transduction > Metabolism > Energy Metabolism

    Signal Transduction > Metabolism > Mitochondrial

    Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria

    亚基Complex I is composed of 45 different subunits This is a component of the iron-sulfur (IP) fragment of the enzyme.
    亚细胞定位Mitochondrion.
    相似性Belongs to the complex I 20 kDa subunit family.
    功能Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.

     

     

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