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- Bioss
- bs-0597P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-0597P |
| 英文名称 | DPPA2 Antibody Blocking Peptide |
| 中文名称 | 多能发育相关基因2封闭多肽 |
| 英文别名 | Developmental Pluripotency Associated 2; developmental pluripotency associated gene2; PESCRG1; Pluripotent embryonic stem cell related protein 1; cancer/testis antigen 100; CT100; developmental pluripotency-associated gene 2; developmental pluripotency-associated protein 2; ECAT15-2; embryonic stem cell (ESC) associated transcript 15-2; PESCRG1; Pluripotent embryonic stem cell related protein 1; Pluripotent embryonic stem cell-related gene 1; Pluripotent embryonic stem cell-related gene 1 protein . |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Embryogenesis > Embryonic stem cells > Surface molecules Developmental Biology > Reproduction > Germ cell markers Stem Cells > Embryonic Stem Cells > Intracellular Stem Cells > Germline Stem Cells > Embryonic Germ Cells |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed abundantly in the central nervous system of adult, but not at all in fetal brain. High levels of SCRG1 transcripts are also observed in testis and aorta. |
| 相似性 | Belongs to the SCRG1 family. |
| 功能 | Dppa2 is a SAP domain protein expressed only in pluripotent cells and the developing germ line. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | SCRG1 (scrapie-responsive protein 1) is a 98 amino acid secreted protein that belongs to the SCRG1 family. The SCRG1 protein contains a 20-amino acid signal peptide, and is expressed abundantly in the central nervous system of human adult, but not at all in fetal brain. The protein is targeted to the Golgi apparatus and large dense-core vesicles/secretory granules in neurons. High levels of SCRG1 transcripts are also observed in testis and aorta. SCRG1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The SCRG1 protein may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. The human and mouse SCRG1 proteins share 83% sequence identity. The SCRG1 gene is conserved in chimpanzee, cow, mouse, rat and chicken, and maps to human chromosome 4q34.1. |
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DPPA2 Antibody Blocking Peptide(bs-0597P)-500ug
￥880
