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- bs-2943P
- 2025年10月16日
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500ug
| 产品编号 | bs-2943P |
| 英文名称 | SEMA6D Antibody Blocking Peptide |
| 中文名称 | 轴突导向因子SEMA6D封闭多肽 |
| 英文别名 | SEM6D_HUMAN; KIAA1479; Q8NFY4; Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Semaphorin 6D. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cell differentiation Neuroscience > Cell Adhesion Proteins > Membrane Proteins Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins |
| 亚细胞定位 | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Isoform 3: Cell membrane; Single-pass type I membrane protein. Isoform 4: Cell membrane; Single-pass type I membrane protein. Isoform 5: Cell membrane; Single-pass type I membrane protein. Isoform 7: Cytoplasm. |
| 相似性 | Belongs to the semaphorin family. Contains 1 PSI domain. Contains 1 Sema domain. |
| 功能 | Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010] |
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SEMA6D Antibody Blocking Peptide(bs-2943P)-500ug
￥880
