- ￥880
- Bioss
- bs-2939P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2939P |
| 英文名称 | RASSF2 Antibody Blocking Peptide |
| 中文名称 | Ras相关结构域蛋白质2封闭多肽 |
| 英文别名 | CENP 34; Centromere protein 34; Ras association (RalGDS/AF 6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain containing protein 2; Ras association domain-containing protein 2; RASF2_HUMAN; RASFADIN; RASSF2; RP4-599I11.1. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors Cancer > Signal transduction > G protein signaling > Small G proteins Cancer > Signal transduction > G protein signaling > Small G proteins > Ras family Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Tumor Suppressors Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators |
| 亚基 | Interacts directly with activated KRAS in a GTP-dependent manner. Interacts (via SARAH domain) with STK3/MST2 AND STK4/MST1. |
| 亚细胞定位 | Nucleus. Cytoplasm. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1. |
| 组织特异性 | Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines. |
| 翻译后修饰 | Phosphorylated by STK3/MST2 and STK4/MST1. |
| 相似性 | Contains 1 Ras-associating domain. Contains 1 SARAH domain. |
| 功能 | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. |
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RASSF2 Antibody Blocking Peptide(bs-2939P)-500ug
￥880
