- ￥580 - 5680
- Bioss
- bs-49050P
- 2025年10月16日
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- 详细信息
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- 规格：
100ug/500ug/20ug
| 规格： | 100ug | 产品价格： | ￥1880.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥5680.0 |
| 规格： | 20ug | 产品价格： | ￥580.0 |
| 产品编号 | bs-49050P |
| 英文名称 | Recombinant CDV Fusion Glycoprotein F0 protein, His |
| 中文名称 | 重组犬瘟热病毒融合糖蛋白F0蛋白 |
| 英文别名 | Canine Distemper Virus Fusion Glycoprotein F0; Fusion glycoprotein F0 · Canine distemper virus (strain Onderstepoort) (CDV); FUS_CDVO; Recombinant CDV Fusion Glycoprotein F0 protein, His |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 52 |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | 10mM Tris-HCl (pH8.0) with 8M Urea and 10% Glycerol. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis |
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Recombinant CDV Fusion Glycoprotein F0 protein, His(bs-49050P)-100ug/500ug/20ug
￥580 - 5680
