DBPA/CSDA1 Antibody Blocking Peptide(bs-12985P)-500ug

DBPA/CSDA1 Antibody Blocking P

eptide(bs-12985P)-500ug
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  • bs-12985P
  • 2025年10月16日
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      500ug

    产品编号bs-12985P
    英文名称DBPA/CSDA1 Antibody Blocking Peptide
    中文名称冷休克蛋白DBPA封闭多肽
    英文别名Cold shock domain containing protein A; Cold shock domain-containing protein A; csdA; CSDA1; DBPA; DNA binding protein A; DNA-binding protein A; Single strand DNA binding protein NF GMB; Single-strand DNA-binding protein NF-GMB; ZO 1 associated nucleic acid binding protein; ZO1 associated nucleic acid binding protein; ZONAB; YBOX3_HUMAN; Y-box-binding protein 3.
    纯化方法HPLC
    亚细胞定位Cytoplasm. Nucleus.
    组织特异性Highly expressed in skeletal muscle and heart.
    相似性Contains 1 CSD (cold-shock) domain.
    功能Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CSDA is a 372 amino acid nuclear and cytoplasmic protein that is highly expressed in skeletal muscle and heart. Containing one CSD (cold-shock) domain, CSDA is thought to bind to GM-CSF promoter, full length mRNA and to short RNA sequences containing a specific consensus site. CSDA is suggested to have a role in translation repression and is found in a mRNP complex with MSY2. MSY2 belongs to the Y-box family of multifunctional proteins that regulate both transcription and translation. CSDA participates in promoting cell proliferation and expression of cyclin D1 and proliferating cell nuclear antigen (PCNA). CSDA is regarded to be an important component of the mechanisms that sense epithelial density and in regulating the switch between proliferation and differentiation through complex transcriptional networks.

     

     

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