CCL12 Antibody Blocking Peptide(bs-21433P)-500ug

CCL12 Antibody Blocking Peptid

e(bs-21433P)-500ug
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  • ¥880
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  • bs-21433P
  • 2025年10月16日
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      500ug

    产品编号bs-21433P
    英文名称CCL12 Antibody Blocking Peptide
    中文名称单核细胞趋化蛋白5封闭多肽
    英文别名MCP5; C-C motif chemokine 12; CCL12; MCP 5; MCP-5; MCP5; Macrophage/monocyte Chemotactic Protein; OTTMUSP00000000792; Scya12; Small inducible cytokine A12.
    纯化方法HPLC
    亚基Homodimer.
    亚细胞定位Secreted.
    组织特异性Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.
    相似性Belongs to the intercrine beta (chemokine CC) family.
    功能Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.

     

     

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