Recombinant human Creatine Kinase B protein(bs-41112P)-100ug/500ug/20ug

Recombinant human Creatine Kin

ase B protein(bs-41112P)-100ug/500ug/20ug
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  • ¥580 - 5680
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  • bs-41112P
  • 2025年10月16日
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      100ug/500ug/20ug

    规格:100ug产品价格:¥1880.0
    规格:500ug产品价格:¥5680.0
    规格:20ug产品价格:¥580.0
    产品编号bs-41112P
    英文名称Recombinant human Creatine Kinase B protein
    中文名称重组人脑型肌酸激酶蛋白
    英文别名B CK; B CK; B-CK; BB-CK; BCK; Brain creatine kinase; Ckb; CKBB; CK-BB; Creatine kinase B; Creatine kinase B chain; Creatine kinase B-type; Creatine Kinase BB Isoenzyme; Creatine Kinase BB Isoenzyme; Creatine Kinase BB Isoenzyme; Creatine kinase brain; Creatine phosphokinase BB; KCRB_HUMAN; Recombinant human Creatine Kinase B protein
    性状Liquid
    纯化方法AC
    理论分子量43
    实际分子量50 kDa
    浓度>0.5 mg/ml
    储存液20mM Tris-HCl (pH8.0) with 150mM NaCl.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy

    Metabolism > Types of disease > Cancer

    Neuroscience > Neurotransmission > Intracellular Signaling > Kinases

    Signal Transduction > Metabolism > Energy Metabolism

    亚基Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
    亚细胞定位Cytoplasmic and Mitochondrial
    相似性Belongs to the ATP:guanido phosphotransferase family.
    Contains 1 phosphagen kinase C-terminal domain.
    Contains 1 phosphagen kinase N-terminal domain.
    功能Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.
    保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The Creatine Kinase MB(CK-MB) isoenzyme is predominantly found in the myocardium (heart muscle). Following a heart attack (myocardial infarction), damaged cells release CK-MB into the blood; these elevated CK levels can be seen 4-8 hours post-infarction and remain elevated for a few days. This makes creatine kinase a useful biomarker for assessing damage to CK-rich tissues, as in cases of rhabdomyolysis (severe muscle breakdown), acute kidney injury, and heart attack.

     

     

    Recombinant human Creatine Kin
    The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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