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500ug
| 产品编号 | bs-2903P |
| 英文名称 | DIRAS3 Antibody Blocking Peptide |
| 中文名称 | 抑癌基因ras同源家族1封闭多肽 |
| 英文别名 | DIRA3; DIRAS family GTP binding RAS like 3; Distinct subgroup of the Ras family member 3; GTP binding protein Di Ras3; NOEY2; Rho related GTP binding protein RhoI; RHOI; DIRA3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors |
| 亚细胞定位 | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). |
| 组织特异性 | Expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. |
| 相似性 | Belongs to the small GTPase superfamily. Di-Ras family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ARHI contains a highly conserved GTP-binding domain, a putative effector domain distinct from that of RAS and RAP proteins, and a C-terminal membrane localization motif. ARHI mRNA is detected in all normal breast and ovarian epithelial cell cultures tested, as well as in normal ovary, heart, liver, pancreas and brain however ARHI expression is down-regulated in breast and ovarian tumors. Reactivation of ARHI expression in breast cancer cells is associated with increased histone H3 acetylation and decreased lysine 9 methylation of histone H3. |
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DIRAS3 Antibody Blocking Peptide(bs-2903P)-500ug
¥880







