DBNDD1 Antibody Blocking Peptide(bs-14202P)-500ug

DBNDD1 Antibody Blocking Pepti

de(bs-14202P)-500ug
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  • ¥880
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  • bs-14202P
  • 2025年10月16日
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      500ug

    产品编号bs-14202P
    英文名称DBNDD1 Antibody Blocking Peptide
    中文名称肌养素结合蛋白1/精神分裂症易感基因封闭多肽
    英文别名DBND1_HUMAN; Dbndd1; Dysbindin (dystrobrevin binding protein 1) domain containing 1; Dysbindin domain-containing protein 1; FLJ12582; MGC3101.
    纯化方法HPLC
    相似性Belongs to the dysbindin family.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料DBNDD1 is a 158 amino acid member of the dysbindin protein family. DBNDD1 is expressed as three isoforms that are produced by alternative splicing and are encoded by a gene mapping to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SGLT-6 as a potential autoimmune modifier.

     

     

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