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- Bioss
- bs-12960P
- 2025年10月16日
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500ug
| 产品编号 | bs-12960P |
| 英文名称 | phospho-beta Adducin (Ser713) Antibody Blocking Peptide |
| 中文名称 | 磷酸化内收蛋白封闭多肽 |
| 英文别名 | beta Adducin (phospho S713); p-beta Adducin (phospho S713); phospho-alpha Adducin(Ser726); phospho-gamma Adducin(Ser693); ADD1; ADD2; ADD3; ADDA; ADDB; ADDL; Adducin 1 (alpha); Adducin 1; Adducin 2 (beta); Adducin 2; Adducin 3 (gamma); Adducin 3; Adducin like; Alpha adducin; Beta adducin. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Blood > Blood Pressure regulation Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins Signal Transduction > Signaling Pathway > Calcium Signaling > Calmodulin Pathway |
| 亚基 | Heterodimer of an alpha and a beta subunit. |
| 亚细胞定位 | Membrane-cytoskeleton-associated protein. |
| 组织特异性 | Expressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line. |
| 翻译后修饰 | The N-terminus is blocked. |
| 相似性 | Belongs to the aldolase class II family. Adducinbn subfamily. |
| 功能 | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. |
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phospho-beta Adducin (Ser713) Antibody Blocking Peptide(bs-12960P)-500ug
￥1080
