CRTAC1 Antibody Blocking Peptide(bs-12948P)-500ug

CRTAC1 Antibody Blocking Pepti

de(bs-12948P)-500ug
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  • bs-12948P
  • 2025年10月16日
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      500ug

    产品编号bs-12948P
    英文名称CRTAC1 Antibody Blocking Peptide
    中文名称软骨酸性蛋白1封闭多肽
    英文别名68 kDa chondrocyte expressed protein; 68 kDa chondrocyte-expressed protein; Acidic secreted protein in cartilage; ASPIC; ASPIC1; Cartilage acidic protein 1; Cartilage acidic protein 1 precursor; CEP 68; CEP-68; CEP68; CRAC1_HUMAN; CRTAC1; Protein CRTAC1-B; W307.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone

    Stem Cells > Mesenchymal Stem Cells > Chondrogenesis

    亚细胞定位Secreted; extracellular space; extracellular matrix.
    组织特异性Expressed in the interterritorial matrix of articular deep zone cartilage (at protein level). Isoform 1 and isoform 2 are expressed in brain. Isoform 1 is detected in lung and chondrocytes. Detected in cartilage, bone, cultured chondrocytes and lung, and at low levels in heart. Not detected in osteoblasts.
    翻译后修饰O-glycosylated.
    相似性Contains 1 EGF-like domain.
    Contains 4 FG-GAP repeats.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CRTAC1 is a 661 amino acid secreted protein. CRTAC1 is O-glycosylated and contains one EGF-like domain and four FG-GAP repeats. Up-regulated in mesenchymal stem cells undergoing chondrogenic differentiation and also by growth factor BMP-4, CRTAC1 is found in the interterritorial matrix of articular deep zone cartilage. CRTAC1 is expressed as three isoforms produced by alternative splicing events. All isoforms are expressed in bone, cartilage and lung, while isoforms 1 and 2 are expressed in the brain. The gene that encodes CRTAC1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome.

     

     

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