CTBS Antibody Blocking Peptide(bs-12937P)-500ug

CTBS Antibody Blocking Peptide

(bs-12937P)-500ug
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  • ¥880
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  • bs-12937P
  • 2025年10月16日
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      500ug

    产品编号bs-12937P
    英文名称CTBS Antibody Blocking Peptide
    中文名称CTBS蛋白封闭多肽
    英文别名Chitobiase di N acetyl; CTB; Di N acetylchitobiase; OTTHUMP00000011570; DIAC_HUMAN.
    纯化方法HPLC
    亚细胞定位Lysosome.
    相似性Belongs to the glycosyl hydrolase 18 family.
    功能Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety.

     

     

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