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- 技术资料
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500ug
| 产品编号 | bs-12937P |
| 英文名称 | CTBS Antibody Blocking Peptide |
| 中文名称 | CTBS蛋白封闭多肽 |
| 英文别名 | Chitobiase di N acetyl; CTB; Di N acetylchitobiase; OTTHUMP00000011570; DIAC_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Lysosome. |
| 相似性 | Belongs to the glycosyl hydrolase 18 family. |
| 功能 | Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety. |
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CTBS Antibody Blocking Peptide(bs-12937P)-500ug
¥880







