- ￥880
- Bioss
- bs-21397P
- 2025年10月16日
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500ug
| 产品编号 | bs-21397P |
| 英文名称 | KIF3A Antibody Blocking Peptide |
| 中文名称 | 驱动蛋白家族蛋白3封闭多肽 |
| 英文别名 | KIF 3; KIF-3; KIF 3A; KIF-3A; KIF3; Kif3a; KIF3A_HUMAN; Kifl; kinesin family member 3A; Kinesin family protein 3; Kinesin family protein 3A; Kinesin like protein KIF 3A; Kinesin like protein KIF3A; Kinesin-like protein KIF3A; Kns3; Microtubule plus end directed kinesin motor 3A; Microtubule plus end-directed kinesin motor 3A. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmitter > Transporters > Other Transporters Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin Signal Transduction > Protein Trafficking > Vesicle Transport > Adapters Stem Cells > Signaling Pathways > Wnt > Surface Molecules |
| 亚基 | Belongs to the kinesin-like protein family. Kinesin II subfamily. Contains 1 kinesin-motor domain. |
| 亚细胞定位 | Cytoplasm, cytoskeleton (Probable). Cell projection, cilium (By similarity). |
| 相似性 | Belongs to the kinesin-like protein family. Kinesin II subfamily. Contains 1 kinesin-motor domain. |
| 功能 | Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate. |
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KIF3A Antibody Blocking Peptide(bs-21397P)-500ug
￥880
