GATB Antibody Blocking Peptide(bs-11667P)-500ug

GATB Antibody Blocking Peptide

(bs-11667P)-500ug
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  • bs-11667P
  • 2025年10月16日
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      500ug

    产品编号bs-11667P
    英文名称GATB Antibody Blocking Peptide
    中文名称细胞色素氧化酶装配因子PET112封闭多肽
    英文别名Cytochrome oxidase assembly factor PET112 homolog; GATB_HUMAN; GLU-ADT subunit B; HSPC199; mitochondrial; PET112; PET112 homolog (yeast); PET112-like; Probable glutamyl-tRNA(Gln) amidotransferase subunit B.
    纯化方法HPLC
    亚基Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (PET112) and C (GATC) subunits.
    亚细胞定位Mitochondrion.
    组织特异性Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle and heart.
    相似性Belongs to the gatB/gatE family. GatB subfamily.
    功能Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料PET112L is the human homolog of the S. cerevisiae COX assembly protein pet112, a protein that is believed to play an important role in the translation of mitochondrial genes. PET112L, also known as HSPC199 or Glu-ADT subunit B (glutamyl-tRNA(Gln) amidotransferase subunit B), is a 557 amino acid protein belonging to the gatB/gatE family of proteins (GatB subfamily) and is believed to play a role in energy metabolism. Localizing to mitochondria, PET112L is expressed in tissues such as heart and muscle, which exhibit high rates of oxidative phosphorylation. The gene encoding PET112L is overexpressed in recurrent ependymoma.

     

     

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