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- Bioss
- bs-11648P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11648P |
| 英文名称 | TMEM59L Antibody Blocking Peptide |
| 中文名称 | 跨膜蛋白59样蛋白封闭多肽 |
| 英文别名 | BSMAP; Brain-specific membrane-anchored protein; C19orf4; TM59L_HUMAN; Tmem59l; Transmembrane protein 59-like. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neurodegenerative disease > Alzheimer's disease > Amyloid Signal Transduction > Protein Trafficking > Golgi Proteins Tags & Cell Markers > Subcellular Markers > Organelles > Golgi |
| 亚细胞定位 | Golgi apparatus membrane. |
| 组织特异性 | Expressed preferentially at high level in the brain. |
| 翻译后修饰 | Belongs to the TMEM59 family. |
| 相似性 | Belongs to the TMEM59 family. |
| 功能 | Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | BSMAP is a 342 amino acid type-I membrane glycoprotein that localizes to organelle membranes and belongs to the TMEM59 family. Expressed at high levels in brain tissue, BSMAP is thought to play a role in brain function and central nervous system activity. The gene encoding BSMAP maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). |
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TMEM59L Antibody Blocking Peptide(bs-11648P)-500ug
￥880
