- ￥880
- Bioss
- bs-11621P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11621P |
| 英文名称 | Guanylin Antibody Blocking Peptide |
| 中文名称 | 鸟苷酸环化酶激活蛋白1封闭多肽 |
| 英文别名 | GapI; GCAP-I; Guanylate cyclase activating protein 1; Guanylate cyclase activator 2A (guanylin 2 intestinal heat-stable); Guanylate cyclase activator 2A; Guanylate cyclase-activating protein 1; Guanylate cyclase-activating protein I; Guanylin; GUC2A_HUMAN; GUCA 2; GUCA2; GUCA2A; STARA. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Growth Factors/Hormones > Hormones Signal Transduction > Second Messenger > Nucleotide Messenger > cGMP |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Highly expressed in ileum and colon. Found in plasma. |
| 相似性 | Belongs to the guanylin family. |
| 功能 | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood. |
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Guanylin Antibody Blocking Peptide(bs-11621P)-500ug
￥880
