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500ug
| 产品编号 | bs-11615P |
| 英文名称 | TAS2R7 Antibody Blocking Peptide |
| 中文名称 | 味觉受体蛋白家族2亚基7封闭多肽 |
| 英文别名 | STC7 4; T2R30; T2R6; T2R7; TA2R7_HUMAN; Tas2r130; Tas2r6; TAS2R7; Taste receptor family B member 4; Taste receptor type 2 member 7; TRB4. |
| 纯化方法 | HPLC |
| 亚基 | Belongs to the G-protein coupled receptor T2R family. |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. |
| 相似性 | Belongs to the G-protein coupled receptor T2R family. |
| 功能 | Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The sense of taste provides animals with valuable information about the quality and nutritional value of food. A family of G protein-coupled receptors are involved in taste perception and include T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Single taste receptor cells express a variety of T2Rs, suggesting that each cell is capable of recognizing multiple tastants. T2R6 (also designatedT2R30, mt2r42, STC 7-4 or taste receptor, type 2, member 130) is an integral membrane receptor protein in mice that may play a role in the perception of bitterness and in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate å-gustducin, mediate PLC-∫-2 activation and lead to the gating of TRPM5. T2R6 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. The human homolog of T2R6, designated T2R7 (TAS2R7, TRB4 or taste receptor, type 2, member 7) is a G protein-coupled receptor expressed in taste receptor cells of the tongue and palate epithelia. |
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TAS2R7 Antibody Blocking Peptide(bs-11615P)-500ug
¥880







