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- Bioss
- bs-1171P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-1171P |
| 英文名称 | Annexin I Antibody Blocking Peptide |
| 中文名称 | 膜粘连蛋白 I封闭多肽 |
| 英文别名 | Annexin I; AnnexinI; Annexin I (lipocortin I); Annexin 1; Annexin-1; Annexin1; AnnexinA1; Annexin A1; AnnexinI; ANX 1; ANX A1; ANX1; ANXA 1; ANXA1; ANXA1 protein; Calpactin 2; Calpactin II; CalpactinII; Chromobindin 9; Chromobindin9; HGNC:533; Lipocortin 1; Lipocortin I; ANXA1_HUMAN; Chromobindin-9; Lipocortin 1; Lipocortin I; Lipocortin1; LipocortinI; Lipocortin1; LipocortinI; LPC 1; LPC1; p35; Phospholipase A2 inhibitory protein. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Annexins Signal Transduction > Signaling Pathway > Calcium Signaling Signal Transduction > Signaling Pathway > Lipid Signaling |
| 亚基 | Homodimer in placenta (20%); linked by transglutamylation. Interacts with DYSF (By similarity). |
| 亚细胞定位 | Nucleus (By similarity). Cytoplasm (By similarity). Cell projection, cilium (By similarity). Basolateral cell membrane (By similarity). Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages (By similarity). |
| 翻译后修饰 | Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity. |
| 相似性 | Belongs to the annexin family. Contains 4 annexin repeats. |
| 功能 | Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a protein that belongs to a family of Ca(2+) dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti inflammatory activity. |
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Annexin I Antibody Blocking Peptide(bs-1171P)-500ug
￥880
