- ￥880
- Bioss
- bs-21362P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-21362P |
| 英文名称 | NCR1 Antibody Blocking Peptide |
| 中文名称 | 细胞毒性受体NK-p46封闭多肽 |
| 英文别名 | Natural killer cell p46-related protein; Natural cytotoxicity triggering receptor 1; NK-p46; NKp46; NK cell-activating receptor; Lymphocyte antigen 94 homolog; CD335; CD 335; LY94; NCTR1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > T Cells > Cytotoxic Cells Signal Transduction > Adapters > Transmembrane |
| 亚基 | Interacts with CD247 and FCER1G |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Selectively expressed by both resting and activated NK cells. |
| 翻译后修饰 | N-glycosylated. O-glycosylated. |
| 相似性 | Belongs to the natural cytotoxicity receptor (NCR) family. Contains 2 Ig-like (immunoglobulin-like) domains. |
| 功能 | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. |
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NCR1 Antibody Blocking Peptide(bs-21362P)-500ug
￥880
