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- Bioss
- bs-41073P
- 2025年10月16日
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- 规格：
100ug/500ug/20ug
| 规格： | 100ug | 产品价格： | ￥1880.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥5680.0 |
| 规格： | 20ug | 产品价格： | ￥580.0 |
| 产品编号 | bs-41073P |
| 英文名称 | Recombinant mouse IL-1b protein, C-His |
| 中文名称 | 重组小鼠IL-1b蛋白 |
| 英文别名 | Catabolin; H1; IL-1β; Hematopoietin 1; IFN beta inducing factor; IL 1; IL 1 beta; IL 1B; IL1B; IL1F2; Interleukin 1 beta; Interleukin 1 beta precursor; LAF; OAF; Osteoclast activating factor; Preinterleukin beta; Pro interleukin 1 beta; IL1B_MOUSE; Interleukin-1 beta; IL-1 beta; Recombinant mouse IL-1b protein, C-His |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 17 |
| 实际分子量 | 26 kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | 10mM Tris-HCl with 500mM NaCl, 300mM Imidazole and 10% Glycerol. |
| 研究领域 | Cardiovascular > Atherosclerosis > Vascular Inflammation > Inflammatory mediators Immunology > Innate Immunity > Cytokines > Interleukins Metabolism > Types of disease > Obesity Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus |
| 亚基 | Monomer. |
| 亚细胞定位 | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
| 相似性 | Belongs to the IL-1 family. |
| 功能 | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]. |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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Recombinant mouse IL-1b protein, C-His(bs-41073P)-100ug/500ug/20ug
￥580 - 5680
