- ￥880
- Bioss
- bs-16925P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16925P |
| 英文名称 | KCTD10 Antibody Blocking Peptide |
| 中文名称 | 钾离子通道多聚体结构域蛋白10封闭多肽 |
| 英文别名 | BTB/POZ domain-containing protein KCTD10; FLJ41739; MSTP028; BACD3_HUMAN; Potassium channel tetramerisation domain containing 10; ULRO61. |
| 纯化方法 | HPLC |
| 亚基 | Component of the BCR(BACURD3) E3 ubiquitin ligase complex, at least composed of CUL3, KCTD10/BACURD3 and RBX1. Interacts with DNA polymerase delta subunit 2/POLD2 (By similarity). Interacts with PCNA. |
| 亚细胞定位 | Nuclear |
| 相似性 | Belongs to the BACURD family. Contains 1 BTB (POZ) domain. |
| 功能 | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KCTD10, a potassium channel tetramerisation domain-containing 10 gene is a novel member of the polymerase delta-interacting protein 1 (PDIP1) gene family. KCTD10 shares significant similarity in amino acid sequence to PDIP1 and can interact with the small subunit of DNA polymerase delta and PCNA as PDIP1 does. Like PDIP1, the expression of KCTD10 gene can be induced by TNF-alpha in NIH3T3 cells. |
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KCTD10 Antibody Blocking Peptide(bs-16925P)-500ug
￥880
