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KCNV2 Antibody Blocking Peptid

e(bs-16921P)-500ug
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  • bs-16921P
  • 2025年10月16日
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    产品编号bs-16921P
    英文名称KCNV2 Antibody Blocking Peptide
    中文名称电压门控钾通道Kv8.2封闭多肽
    英文别名KCNV2; KCNV2_HUMAN; KV11.1; Kv8.2; MGC120515; Potassium channel subfamily V member 2; Potassium voltage-gated channel subfamily V member 2; RCD3B; Voltage-gated potassium channel Kv8.2; Voltage-gated potassium channel subunit Kv8.2.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > Potassium Channels

    Neuroscience > Sensory System > Visual system

    亚基Heteromultimer with KCNB1, KCNC1 and KCNF1. Does not form homomultimers.
    亚细胞定位Cell membrane. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.
    组织特异性Detected in lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary and colon.
    相似性Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.2/KCNV2 sub-subfamily.
    功能Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008]

     

     

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