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500ug
| 产品编号 | bs-16920P |
| 英文名称 | KCNV1 Antibody Blocking Peptide |
| 中文名称 | 电压门控钾通道亚基Kv8.1封闭多肽 |
| 英文别名 | KCNV1; KCNV1_HUMAN; Neuronal potassium channel alpha subunit HNKA; Potassium voltage gated channel subfamily V member 1; Potassium voltage-gated channel subfamily V member 1; Voltage gated potassium channel subunit Kv8.1; Voltage-gated potassium channel subunit Kv8.1 |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane. Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2. |
| 组织特异性 | Detected in brain. |
| 翻译后修饰 | Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity. |
| 相似性 | Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily. |
| 功能 | Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This protein is essentially present in the brain, and its role might be to inhibit the function of a particular class of outward rectifier potassium channel types. [provided by RefSeq, Jul 2008] |
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KCNV1 Antibody Blocking Peptide(bs-16920P)-500ug
¥880







