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- Bioss
- bs-1691P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1691P |
| 英文名称 | HCN4 Antibody Blocking Peptide |
| 中文名称 | 环化核苷酸调控阳离子通道蛋白亚型4 |
| 英文别名 | HCN 4;Hyperpolarization activated cyclic nucleotide gated potassium channel 4; Potassium/sodium hyperpolarization activated cyclic nucleotide gated channel 4;Hyperpolarization activated Cyclic Nucleotide-gated channel 4; HCN4_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Heart > Cardiac arrhythmias Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > More Channels Neuroscience > Neurotransmission > Receptors / Channels > More Ion Channels Neuroscience > Sensory System > Taste system |
| 亚基 | The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits. |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Highly expressed in thalamus, testis and in heart, both in ventricle and atrium. Detected at much lower levels in amygdala, substantia nigra, cerebellum and hippocampus. |
| 相似性 | Belongs to the potassium channel HCN family. Contains 1 cyclic nucleotide-binding domain. |
| 功能 | Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) and in neurons (Ih). Activated by cAMP. May mediate responses to sour stimuli. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HCN4 is a member of the family of hyperpolarization activated and cyclic nucleotide gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node. |
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HCN4 Antibody Blocking Peptide(bs-1691P)-500ug
￥880
