RAB11FIP4 Antibody Blocking Peptide(bs-21127P)-500ug

RAB11FIP4 Antibody Blocking Pe

ptide(bs-21127P)-500ug
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  • bs-21127P
  • 2025年10月16日
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      500ug

    产品编号bs-21127P
    英文名称RAB11FIP4 Antibody Blocking Peptide
    中文名称G蛋白结合蛋白RAB相互作用蛋白4封闭多肽
    英文别名Rab11 family interacting protein 4; RAB11 FIP4; Rab11 FIP4 like; RGD1305063; RP23-271B20.4.
    纯化方法HPLC
    亚基Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction is direct. Forms a heterooligomeric complex with RAB11FIP2, RAB11FIP3 and RAB11FIP5. Interacts with HCMV (human cytomegalovirus) gM/UL100. Interacts with ECM29.
    组织特异性Recycling endosome membrane; Peripheral membrane protein. Note: Colocalizes with RAB11A in the endocytic recycling compartment (ERC).
    功能Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Apr 2008]

     

     

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