FUT3 Antibody Blocking Peptide(bs-12870P)-500ug

FUT3 Antibody Blocking Peptide

(bs-12870P)-500ug
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  • ¥880
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  • bs-12870P
  • 2025年10月16日
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      500ug

    产品编号bs-12870P
    英文名称FUT3 Antibody Blocking Peptide
    中文名称血型Lewis A抗原封闭多肽
    英文别名Lewis A antigen.
    纯化方法HPLC
    亚细胞定位Plasma membrane - adsorbed onto the surface of erythrocytes.
    组织特异性Highly expressed in stomach, colon, smallintestine, lung and kidney and to a lesser extent in salivarygland, bladder, uterus and liver.
    相似性Belongs to the glycosyltransferase 10 family.
    功能Blood group Lewis b is a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Blood Group Lewis b is a carbohydrate determinant carried on both glycolipids and glycoproteins.

     

     

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