- ￥880
- Bioss
- bs-12864P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12864P |
| 英文名称 | Betacellulin Antibody Blocking Peptide |
| 中文名称 | β细胞素封闭多肽 |
| 英文别名 | Beta cellulin; Beta cellulin precursor; BTC; BTC_HUMAN; OTTHUMP00000160600; OTTHUMP00000219057; Probetacellulin. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Growth Factors/Hormones > EGF |
| 亚基 | Monomer. Interacts with EGFR and ERBB4. |
| 亚细胞定位 | Cell membrane and Secreted > extracellular space. |
| 组织特异性 | Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. |
| 相似性 | Contains 1 EGF-like domain. |
| 功能 | Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Betacellulin Antibody Blocking Peptide(bs-12864P)-500ug
￥880
