CYP51A1 Antibody Blocking Peptide(bs-15409P)-500ug

CYP51A1 Antibody Blocking Pept

ide(bs-15409P)-500ug
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  • bs-15409P
  • 2025年10月16日
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      500ug

    产品编号bs-15409P
    英文名称CYP51A1 Antibody Blocking Peptide
    中文名称羊毛甾醇14α-去甲基化酶蛋白封闭多肽
    英文别名Lanosterol 14-alpha demethylase; LDM; CYPLI; Cytochrome P450 51A1; Cytochrome P450-14DM; Cytochrome P45014DM; Cytochrome P450LI; Sterol 14-alpha demethylase; CP51A_HUMAN.
    纯化方法HPLC
    研究领域

    Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cytochromes

    Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Cholesterol Metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Cytochromes

    Signal Transduction > Metabolism > Drug metabolism

    Signal Transduction > Metabolism > Lipid metabolism

    亚细胞定位Endoplasmic reticulum membrane (Potential). Microsome membrane (Potential).
    组织特异性Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung.
    相似性Belongs to the cytochrome P450 family.
    功能Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-Methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

     

     

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